FEATURES OF THE COURSE OF INTRACEREBRAL COMPLICATED HEMISPHERIC CEREBRAL STROKE IN PATIENTS WITH HYPERTENSIVE DYSCIRCULATORY ENCEPHALOPATHY

  • Volodymyr Dariy Doctor of Medical Sciences, Professor of the Department of Nervous Diseases of the Zaporizhzhia State Medical University
  • Olexandr Stoyanov Professor of Neurology Department, Odessa National Medical University
  • Olena Hryhorieva MD, PhD, DSc, professor, Head of the Department of Human Anatomy, Operative Surgery and Topographic Anatomy Zaporizhzhia State Medical University
  • Iryna Vizir ZSMU, assistant professor
  • Maryna Sikorska ZSMU, assistant professor
  • Nataliia Tomakh Medical center of the Limited Liability Company “INET-09”
Keywords: ischemic, cerebral stroke, hypertensive dyscirculatory encephalopathy

Abstract

Relevance. Cerebral strokes (CS) in the structure of the causes of death of the population occupy the third place after coronary heart disease and malignant neoplasms.

The aim of the study was to identify new structural clinical and pathomorphological features of secondary brainstem syndrome (SBS) depending on the presence of complications of cerebral hemispheric stroke and hypertensive dyscirculatory encephalopathy.

Materials and methods. 201 patients were observed with complicated MI: 91 with hemorrhagic (HS) and 110 with ischemic (IS). Of these, 102 are women and 99 are men between the age of 44 and 72. The study used: clinical, radiological, histological and statistical methods.

Study results. Comparing the frequency of intracerebral complications and the severity of the subgroup with an abortive course and the group with the classic picture of SBS, it can be noted that the highest frequency of complications and unfavorable outcomes was observed in persons with the classic course of SBS, in 84 out of 128 patients (65.6%); then in persons with a predominant lesion of the nonspecific reticular systems of the brainstem – in 22 out of 43 (51.2%); and only 11 out of 30 (36.7%) patients with focal secondary stem manifestations
had a lethal outcome.

Conclusions. Two variants of the abortive course of SBS have been identified, which have not only a clinical, but also a pathomorphological basis: the first with social symptoms, in which there is a deep lesion of the reticulobrainstem structures; the second with a clinically delineated focal stem picture, in which a more pronounced nuclear lesion of the cranial nerves develops. The selected variants of the course allow expanding the clinical and pathomorphological understanding of the SBS, more accurately predicting its outcomes, which may be important in the management of patients with complicated cerebral stroke.

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Published
2022-05-31
How to Cite
Dariy, V., Stoyanov, O., Hryhorieva, O., Vizir, I., Sikorska, M., & Tomakh, N. (2022). FEATURES OF THE COURSE OF INTRACEREBRAL COMPLICATED HEMISPHERIC CEREBRAL STROKE IN PATIENTS WITH HYPERTENSIVE DYSCIRCULATORY ENCEPHALOPATHY. Immunology and Allergology: Science and Practice, (4), 34-38. https://doi.org/10.37321/immunology.2021.4-03