PROTEOLYSIS IN THE PATHOGENESIS OF ALLERGIC DISEASE

  • Олексій Гарєєв Director of the Production company “Simesta”
  • Тетяна Кравець Production Manager at “Production company “Simesta”.
  • Катерина Лобанова head of the serological department at “Production company “Simesta”.
Keywords: proteolysis, microbiome, pathogenesis of allergic disease, electrophoregram.

Abstract

In the proposed study, the results of cultivating microorganisms that are part of the transient and normoflora of the human intestine, with proteins extracted from food, which are commonly included in the daily diet, were evaluated. An extract of cow’s milk proteins, extracts of chicken yolk proteins, chicken protein, soy, wheat, and peanuts were taken in the experiment. All strains of microorganisms are probiotic, which, as biologically active additives (BAA), are widely used in various formulations as a means of therapy. Confirmation was obtained of the participation of extracellular proteolytic enzymes of the studied microorganisms in the degradation of food proteins. The selectivity of the effect of enzymes of one strain on various food proteins was noted; participation in the hydrolysis of a specific protein of proteases of strains of various taxonomic group.

Published
2022-09-09
How to Cite
Гарєєв, О., Кравець, Т., & Лобанова, К. (2022). PROTEOLYSIS IN THE PATHOGENESIS OF ALLERGIC DISEASE. Immunology and Allergy: Science and Practice, (1-2), 29-43. https://doi.org/10.37321/immunology.2022.1-2-04