SEROPREVALENCE OF ANTI-MEASLES IGG IN THE POPULATION OF KHARKIV REGION IN 2018-2019

  • Igor Yudin Candidate of Medical Sciences, Senior Researcher of the laboratory of immunoreabilitology State Institution “Mechnikov Institute of Microbiology and Immunology NAMS of Ukraine”, str. Pushkinska, 14-16, Kharkiv, Ukraine, 61057
  • Irina Kuchma Candidate of Medical Sciences, Senior Fellow, Researcher at the Laboratory of Clinical Immunology and Allergology, State Institution “Mechnikov Institute of Microbiology and Immunology NAMS of Ukraine”, str. Pushkinska, 14-16, Kharkiv, Ukraine, 61057
  • Andriy Voliansky Doctor of Medical Sciences, Senior Fellow, Head of the Laboratory of Immunoreabilitology State Institution “Mechnikov Institute of Microbiology and Immunology NAMS of Ukraine”, str. Pushkinska, 14-16, Kharkiv, Ukraine, 61057

Abstract

Aim. The aim of this study was to evaluate herd immunity against measles in different age groups of the Kharkiv region of Ukraine’s population.

Materials and methods. Seroprevalence of specific IgG antibodies was studied among different age groups of the Kharkiv region population from February 2018 to July 2019 by ELISA method.

Results. A number of 6564 sera samples were processed. The overall seropositivity level was 91.3%; negative results were 5.3% and 3.3% equivocal. The highest seropositivity for IgG (> 98%) was in people aged 50 years and older. The lowest seropositivity rates were observed in the cohorts of 20-29 years (87.2%), 30-39 years (86.9%), and 40-49 years (91.1%).

Conclusions. Measles-susceptible populations were identified for which new prevention strategies should be applied in the form of personalized vaccination campaigns to increase herd immunity.

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Published
2019-12-23
How to Cite
Yudin, I., Kuchma, I., & Voliansky, A. (2019). SEROPREVALENCE OF ANTI-MEASLES IGG IN THE POPULATION OF KHARKIV REGION IN 2018-2019. Immunology and Allergy: Science and Practice, (4), 22-25. https://doi.org/10.37321/immunology.2019.04-03